October 26, 2011
Betz cells, a type of pyramidal cell neurons located in the grey matter of the brain, are the largest neurons in the central nervous system, sometimes reaching 100μm in diameter.

Betz cells, a type of pyramidal cell neurons located in the grey matter of the brain, are the largest neurons in the central nervous system, sometimes reaching 100μm in diameter.

October 25, 2011
purkinje cells (some of the largest neurons in the human brain—the largest are coming up soon)

purkinje cells (some of the largest neurons in the human brain—the largest are coming up soon)

October 24, 2011
oculomotor neurons (colored with the brainbow technique)

oculomotor neurons (colored with the brainbow technique)

October 24, 2011
more Brainbow! this is the brain stem. 

more Brainbow! this is the brain stem. 

October 23, 2011
So this is an amazing thing we talked about in bio the other day. It’s a method called Brainbow. It’s really hard to track neurons when they can get so long and tangly, as you can see in this light microscopy of a mouse hippocampus, so scientists can mark each neuron with a different color of fluorescence via transgenes that produce fluorescent proteins. What a brilliant solution! 

So this is an amazing thing we talked about in bio the other day. It’s a method called Brainbow. It’s really hard to track neurons when they can get so long and tangly, as you can see in this light microscopy of a mouse hippocampus, so scientists can mark each neuron with a different color of fluorescence via transgenes that produce fluorescent proteins. What a brilliant solution! 

October 5, 2011
from wikipedia:
Neuron from Chicken embryo photographed with confocal microscope after being dyed.

from wikipedia:

Neuron from Chicken embryo photographed with confocal microscope after being dyed.

October 2, 2011
mouse neuron

mouse neuron

June 11, 2011
deep dissection of brain stem, lateral view

deep dissection of brain stem, lateral view

June 10, 2011
Superficial dissection of brain-stem. Ventral view. (“Cerebral peduncle” visible in red at center-right.)

Superficial dissection of brain-stem. Ventral view. (“Cerebral peduncle” visible in red at center-right.)

May 31, 2011
The multicolored neurons sit in the cerebral cortex, which is involved in higher thought processes and sensory perception. To create a unique color in each neuron, Lichtman did some clever genetic tinkering: He inserted the genes for different-colored fluorescent proteins into the mouse’s genome so that each neuron would randomly express a combination of the genes. It ends up being a game of chance: Each neuron is essentially pulling the lever on a “molecular slot machine,” says team member Jean Livet, receiving a random combination of the genes that endow it with one of 90 possible colors.

The multicolored neurons sit in the cerebral cortex, which is involved in higher thought processes and sensory perception. To create a unique color in each neuron, Lichtman did some clever genetic tinkering: He inserted the genes for different-colored fluorescent proteins into the mouse’s genome so that each neuron would randomly express a combination of the genes. It ends up being a game of chance: Each neuron is essentially pulling the lever on a “molecular slot machine,” says team member Jean Livet, receiving a random combination of the genes that endow it with one of 90 possible colors.

May 11, 2011
micrograph of the cerebellum

micrograph of the cerebellum

May 10, 2011
micrograph of the cerebellum

micrograph of the cerebellum

May 10, 2011
micrograph of the cerebellum

micrograph of the cerebellum

May 9, 2011
purkinje cell

purkinje cell

May 4, 2011
Thin section of diseased cat brain (250x)

Thin section of diseased cat brain (250x)

5:28pm
  
Filed under: science animals biology cat brain cells