This is a photograph I took of a neuron which has been differentiated from an embryonic carcinoma cell (P19 cell line), using retinoic acid.
submission from michellethebelle
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(a science blog)
my other blogs faq other science blogs talk to me submit lovely photos
December 20, 2011
October 26, 2011
Betz cells, a type of pyramidal cell neurons located in the grey matter of the brain, are the largest neurons in the central nervous system, sometimes reaching 100μm in diameter.
October 25, 2011
purkinje cells (some of the largest neurons in the human brain—the largest are coming up soon)
October 24, 2011
October 24, 2011
October 23, 2011
So this is an amazing thing we talked about in bio the other day. It’s a method called Brainbow. It’s really hard to track neurons when they can get so long and tangly, as you can see in this light microscopy of a mouse hippocampus, so scientists can mark each neuron with a different color of fluorescence via transgenes that produce fluorescent proteins. What a brilliant solution!
September 25, 2011
May 31, 2011
The multicolored neurons sit in the cerebral cortex, which is involved in higher thought processes and sensory perception. To create a unique color in each neuron, Lichtman did some clever genetic tinkering: He inserted the genes for different-colored fluorescent proteins into the mouse’s genome so that each neuron would randomly express a combination of the genes. It ends up being a game of chance: Each neuron is essentially pulling the lever on a “molecular slot machine,” says team member Jean Livet, receiving a random combination of the genes that endow it with one of 90 possible colors.
April 17, 2011
April 12, 2011
