October 26, 2011
Betz cells, a type of pyramidal cell neurons located in the grey matter of the brain, are the largest neurons in the central nervous system, sometimes reaching 100μm in diameter.

Betz cells, a type of pyramidal cell neurons located in the grey matter of the brain, are the largest neurons in the central nervous system, sometimes reaching 100μm in diameter.

October 24, 2011
oculomotor neurons (colored with the brainbow technique)

oculomotor neurons (colored with the brainbow technique)

October 24, 2011
more Brainbow! this is the brain stem. 

more Brainbow! this is the brain stem. 

October 23, 2011
So this is an amazing thing we talked about in bio the other day. It’s a method called Brainbow. It’s really hard to track neurons when they can get so long and tangly, as you can see in this light microscopy of a mouse hippocampus, so scientists can mark each neuron with a different color of fluorescence via transgenes that produce fluorescent proteins. What a brilliant solution! 

So this is an amazing thing we talked about in bio the other day. It’s a method called Brainbow. It’s really hard to track neurons when they can get so long and tangly, as you can see in this light microscopy of a mouse hippocampus, so scientists can mark each neuron with a different color of fluorescence via transgenes that produce fluorescent proteins. What a brilliant solution! 

May 31, 2011
The multicolored neurons sit in the cerebral cortex, which is involved in higher thought processes and sensory perception. To create a unique color in each neuron, Lichtman did some clever genetic tinkering: He inserted the genes for different-colored fluorescent proteins into the mouse’s genome so that each neuron would randomly express a combination of the genes. It ends up being a game of chance: Each neuron is essentially pulling the lever on a “molecular slot machine,” says team member Jean Livet, receiving a random combination of the genes that endow it with one of 90 possible colors.

The multicolored neurons sit in the cerebral cortex, which is involved in higher thought processes and sensory perception. To create a unique color in each neuron, Lichtman did some clever genetic tinkering: He inserted the genes for different-colored fluorescent proteins into the mouse’s genome so that each neuron would randomly express a combination of the genes. It ends up being a game of chance: Each neuron is essentially pulling the lever on a “molecular slot machine,” says team member Jean Livet, receiving a random combination of the genes that endow it with one of 90 possible colors.

May 11, 2011
micrograph of the cerebellum

micrograph of the cerebellum

May 10, 2011
micrograph of the cerebellum

micrograph of the cerebellum

May 10, 2011
micrograph of the cerebellum

micrograph of the cerebellum

April 24, 2011
differences in the brain’s serotonin system in females and males.
females and males differ in terms of the number of binding sites for serotonin in certain parts of the brain. this may account for the higher occurrence of depression and anxiety in females.  

differences in the brain’s serotonin system in females and males.

females and males differ in terms of the number of binding sites for serotonin in certain parts of the brain. this may account for the higher occurrence of depression and anxiety in females.  

(Source: images.sciencedaily.com)